The site of Guado San Nicola at Monteroduni was first brought to notice in 2005 when the sig.ra Leone, owner of the land, found a biface lithic and a number of other retouched stone artefacts.

The first archaeological investigation took place in 2008, followed by an excavation in 2009 which aimed to gain further knowledge of the paleolithic site. Given the particular typology of the finds this site provides a useful reference point for the reconstruction of the methods of land exploitation and the settlement strategies adopted by the groups of prehistoric men in the Monteroduni area.

An area of circa 40 m2 was investigated revealing a stratigraphic sequence constituted by a succession of levels of fluvial-lacustral origin (gravels, sands and clays) alternating with sediments of volcanic origin (tufa), some in primary deposition, containing paleontological and prehistoric material.

The site was characterised by the discovery, in a relatively restricted area, of an abundant lithic industry of Acheulean attribution, characterised by the presence of numerous biface tools (about 50) associated with flakes, cores, tools and hammerstones. The biface tools were constituted by complete tools, points and proximal fragments, of extremely variable dimensions probably in relation to the morphology of the raw material used and the amount of retouching undertaken. They were characterised by the accurate preparation of the points and of at least one of the edges.

The stone artefacts had been made using stone and bone (deer antlers) hammers, flint striking platforms such as small slabs, small limestone blocks, and small to medium limestone cobbles. Only in a few cases did the collected materials shown slight signs of having been washed down a river.
The faunal material was characterised by the presence of dental and diaphisis fragments. Numerous antler remains were also present in the form of basal, rod and dagger fragments.
The paleontological analyses of the macrovertebrate remains revealed the presence of deer, elephant, aurochs, Merk rhinoceros, horse and bear. The cervids in general were numerous, represented by antlers attributable to small deer (e.g. roe and fallow deer) and very large specimens such as the megaceros.

Therefore, this was fauna from a warm climate where the river was certainly a geomophological element of great importance. The presence of large herbivores was favoured by open vegetation rich in pastures, which allowed horses and pachyderms to survive, whilst in the wetter areas the vegetation was thicker providing cover for cervids and rhinoceros.

As regards evidence of human activity, intentional fracturing was seen on diverse fragments of diaphises and on one fragment of auroch radius. The latter also showed a thin linear striation sub-parallel to the long axis of the bone resulting from an intentional cut made with a lithic tool.