The investigation covered an area of about 40 m2 and identified a stratigraphic sequence comprising a succession of levels of fluvio-lacustrine origin (gravels, sands, and clays), interspersed with volcanic sediments (tufts and cinerites) also in primary deposition, containing paleontological and prehistoric material.

The deposit contained abundant lithic industry characterised by flakes, cores, tools and hammers, above all a substantial number of bifacial tools (about 100), implements typical of the Acheulean period that are often difficult to find and whose function is much debated.

Abundant faunal remains were associated with the lithic industry, suggesting the presence in the ancient landscape of large herbivores including deer, bovines, horses, rhinoceros, and elephants.
These species would have lived in an open environment in which the river (the present Volturno) also represented a vital point of reference for groups of humans. The presence of large herbivores was favoured by open vegetation, rich in pastures suitable for horses and pachyderms, while in the more humid areas the vegetation was denser and provided refuge for deer and rhinos.
Butchery marks were present on animal bones, caused by the stone tools used to remove the flesh, and some bones had been deliberately fractured so that the marrow could be removed.

As well as representing an important point of reference for Italian and European prehistory with regard to bifacial tools, the site of Guado S. Nicola is of great interest with regard to geology as it can be defined a_geosite_, that is, a natural asset of particular scientific value characterised by the presence of natural elements providing invaluable contributions to the understanding of the territory’s (not only the Molise) geological history.