In July 2013, the University of Ferrara carried out geological and pedological investigations in the area of the site of Guado San Nicola (Monteroduni, Isernia). Particular attention was focused on the stratigraphy and samples were taken for laboratory analysis. A sondage was opened at the top of the terrace on which the finds were made.

This intervention improved knowledge of the clearly divided stratigraphy that was over two metres deep, situated on the fluvial terrace at the end of the ancient fan of the Lorda Torrent. The base of the sequence was formed by coarse alluvial sediments that indicated a course formed by intertwined channels in rapid aggradation during a cold and arid climatic phase. At the top of the deposit, the archaeological levels were contained in alternating gravelly and sandy layers, some with pyroclastic sediment. The sedimentary structures indicated wandering courses or meanders and thus indicate a substantial improvement in climate. A heavily leached and rubefied paleo-surface was present at the top of the sequence. The lithic, morphological, and pedological-stratigraphical evidence seemed to suggest the context related to the Final Interglacial period, but the dating of the three overlying litho-stratigraphic units carried out using the 40Ar/39Ar method on sanidine crystals gave the following results: unit US C (400±9 ka), US B (379±8 ka) and US TUFO (345±9 ka). The antiquity of the site was confirmed by a combined uranium-thorium (U-TH) and electron spin resonance (ESR) dating carried out on six horse and rhinoceros teeth from the archaeological levels in US C and B. An average age of 364±36 ka was obtained, and in accordance with the 40Ar/39Ar dating would seem to suggest the attribution of the context to the end of the MIS 11. Such an attribution was also confirmed by the presence of Cervus elaphus acoronatus and by the technical and typological characteristics of the lithic industry recovered.

The faunal assemblage from US C and B also included Ursus sp., Elephas sp., Equus sp., Stephanorhinus kirchbergensis, Megaloceros sp., Cervus elaphus acoronatus, and Bos primigenius, which indicates that the climate was temperate to hot. The paleontological finds were characterized by the presence of striations and intentional breaks produced during the removal of the bone marrow and meat. The abundance of shed deer antlers seemed to relate to their use as hammers for flaking lithics.

The lithics recovered from US C and B were affected by the sedimentary processes. This phenomenon was less noticeable for the materials in US B, which were well-preserved although they had suffered slight dislocation and redistribution. The finds had been obtained from the use of poor quality plates that showed the presence of intrusions and preferential fracturing surfaces. Bifacial flints of varying shapes and sizes, often well-worked at the pointed end and almost always with an un-worked base were common. The chipped striking platforms were characterized by the presence of Levallois artefacts. Lithics on limestone striking platforms were also found.